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Cerebral Aneurysms

Cerebral Aneurysms

Description

Within this project, the development of a methodology for the patient specific analysis of cerebral aneurysms is in focus. Such a cerebral aneurysm is potentially life-threatening. Every year, about 10 out of 100,000 people suffer a spontanious rupture, with a mortality of 50%. For the patients and their attending physicians, a sensible estimation of the rupture risk and the best strategy of treatment is of great importance. We believe that an analysis based on the individual geometry of an aneurysm, and the predicted biofluidmechanical properties can provide insight into this matter. Here, we especially deal with the segmentation, reconstruction and visualization of aneurysms. Further information is available in the detailed project description.

Members

Responsible

Partners

Charité Berlin, Labor für Biofluidmechanik, Thielallee 73, 14195 Berlin (Leonid Goubergrits, Klaus Affeld)
Helios Klinikum Berlin, Hobrechtsfelder Chaussee 96, 13125 Berlin (Andreas Spuler)

Funding

DFG HE 2948/5-1 (04/2007 - 03/2009)
DFG HE 2948/5-3 (01/2011 - 12/2013)

Duration

04/2007-12/2013

 

Publications

  • Christoph Petz, Kai Pöthkow, Hans-Christian Hege. Probabilistic Local Features in Uncertain Vector Fields with Spatial Correlation. Computer Graphics Forum, 31(3): 1045 – 1054, 2012.
  • Leonid Goubergrits, Jens Schaller, Ulrich Kertzscher, Nils van den Bruck, Kai Pöthkow, Christoph Petz, Hans-Christian Hege, Andreas Spuler. Statistical wall shear stress maps of ruptured and unruptured middle cerebral artery aneurysms. J. R. Soc. Interface, 9(69):677 – 688, 2012.
  • Leonid Goubergrits, Heinrich Hoch, Hans-Christian Hege, Christoph Petz, Klaus Affeld, Ulrich Kertzscher, Jens Poethke, André Berthe, Bente Thamsen, Andreas Spuler. In Vitro Study of Near-Wall Flow in a Cerebral Aneurysm Model with and without Coils. American Journal of Neuroradiology, 31(8):1521 – 1528, 2010.
  • Olufemi Rosanwo, Christoph Petz, Steffen Prohaska, Ingrid Hotz, Hans-Christian Hege. Dual Streamline Seeding. Proc. Pacific Vis '09, p. 9–16, 2009.
  • Olufemi Rosanwo, Christoph Petz, Steffen Prohaska, Ingrid Hotz, Hans-Christian Hege. Dual Streamline Seeding - Method and Implementation. Technical Report ZR-08-49, Zuse Institute Berlin, 2008.
  • Leonid Goubergrits, Sarah Weber, Christoph Petz, Andreas Spuler, Jens Pöthke, André Berthe, Hans-Christian Hege. Wall-PIV as a Near Wall Flow Validation Tool for CFD. Journal of Visualization, 12(3), 2009.
  • Leonid Goubergrits, Ernst Wellnhofer, Ulrich Kertzscher, Klaus Affeld, Christoph Petz, Hans-Christian Hege. Coronary Artery WSS Profiling Using a Geometry Reconstruction Based on Biplane Angiography. Annals of Biomedical Engineering, 37(4):682–691, 2009.
  • Christoph Petz, Steffen Prohaska, Leonid Goubergrits, Ulrich Kertzscher, Hans-Christian Hege. Near-Wall Flow Visualization in Flattened Surface Neighborhoods. Proc. Simulation and Visualization 2008, p. 93–105, Magdeburg, Germany, 2008.
  • Leonid Goubergrits, Ulrich Kertzscher, Klaus Affeld, Christoph Petz, Detlev Stalling, Hans-Christian-Hege. Numerical Dye Washout Method as a Tool for Characterizing the Heart Valve Flow: Study of Three Standard Mechanical Heart Valves. ASAIO Journal, 54(1):50-57, 2008.
  • Leonid Goubergrits, Jens Pöthke, Christoph Petz, Hans-Christian Hege, Andreas Spuler, Ulrich Kertzscher. 3D Bildgebung von zerebralen Aneurysmen. Bildverarbeitung für die Medizin, p. 153–157, 2008.
  • Leonid Goubergrits, Tobias Timmel, Klaus Affeld, Christoph Petz, Detlev Stalling, Hans Christian Hege. Characterization of an artificial valve flow using the numerical dye washout visualization technique: Application to the monoleaflet valve with purged flow. Artificial Organs, 30(8):642-650, 2006.
  • Christoph Petz, Detlev Stalling, Leonid Goubergrits, Klaus Affeld, Andreas Spuler. Validierung von Strömungssimulationen in kardiovaskulären Anwendungen. Bildverabeitung für die Medizin 2004, p. 356-360, 2004.
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