SiBill
Simulated Biomechanics of the Lower Limb
Description
As part of the Collaborative Research Centre 760 - "Biomechanics and Biology of Musculoskeletal Regeneration" - the goal of this project is to reconstruct patient specific 3D anatomy models of the human lower limb from medical image data. The central problem addressed by the Collaborative Research Centre (SFB) 760 initiative is the healing and regeneration of bone. The long term goal is the understanding of endogenous formation of biologically and mechanically competent bone. A key question to be answered is: "What are the physical mechanisms that allow the regeneration of such competent bone?" On the way to answering that question, patient specific musculoskeletal function and loading conditions have to be characterised. For that purpose, individual models of the lower limb anatomy are a basic prerequisite. Further information is available in the detailed project description.
Members
Responsible
Partners
Julius Wolff Institute, Charité University Medicine, Berlin, Germany (Prof. Dr. Georg Duda, Dr. Markus Heller)
Biomechanics Laboratory, Charité University Medicine, Department of Orthopaedics, Berlin, Germany
Clinic for Rheumatology and Clinical Immunology, Charité University Medicine, Berlin, Germany
Institute for Medical Genetics, Charité University Medicine, Berlin, Germany
Free University Berlin, Institute for Chemistry-Biochemistry, Berlin, Germany (Prof. Dr. Petra Knaus)
Free University Berlin, Institute for Mathematics II, Berlin, Germany
Max Planck Institute of Colloids and Interfaces, Department of Biomaterials, Golm, Germany (Prof. Dr. Peter Fratzl)
Max Planck Institute for Molecular Genetics, Group Development and Disease, Berlin, Germany (Prof. Dr. Stefan Mundlos)
German Rheumatism Research Center (DRFZ), Berlin, Germany
Helmholtz-Zentrum Geesthacht, Institute of Polymer Research, Centre for Biomaterial Development, Teltow, Germany (Prof. Dr. Andreas Lendlein)
Funding
German Research Foundation (DFG) (01/2007-12/2011)
Duration
since 01/2007
Further Information