Image-based Analysis of in vivo Knee Dynamics
The aim of this project is the development of MRI-based methods and technologies for the non-invasive in-vivo assessment of mechanical loads in soft tissue structures of the knee joint. Such an in-vivo assessment of soft tissue kinematics in 3D together with their incident loads would pave the way for an understanding of the dynamics of elastic deformations of tendons, ligaments, and menisci in healthy subjects as well as their changes due to pathologies (e.g. after ruptures of the anterior cruciate ligament in young vs. elderly patients). Given the short acquisition times available in the dynamic imaging setup only partial information (low resolution, 2D slices instead of 3D volume) can be acquired. Therefore, specialized reconstruction methods have to be developed to extract the motion of soft tissues from the incomplete data, e.g. by correlating information from high-resolution static images to the partial data. The obtained time-dependent configurations of the structures can then be interpreted as shape trajectories allowing morphometric analysis employing manifold-valued statistical tools.
Publications
2019 |
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Martin Krämer, Marta Maggioni, Nicholas Brisson, Stefan Zachow, Ulf Teichgräber, Georg Duda, Jürgen Reichenbach | T1 and T2* mapping of the human quadriceps and patellar tendons using ultra-short echo-time (UTE) imaging and bivariate relaxation parameter-based volumetric visualization | Magnetic Resonance Imaging, 63(11), pp. 29-36, 2019 |
BibTeX
DOI |
2018 |
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Martin Krämer, Marta Maggioni, Christoph von Tycowicz, Nick Brisson, Stefan Zachow, Georg N Duda, Jürgen Reichenbach | Ultra-short echo-time (UTE) imaging of the knee with curved surface reconstruction-based extraction of the patellar tendon | ISMRM (International Society for Magnetic Resonance in Medicine), 26th Annual Meeting 2018, Paris, France, 2018 |
BibTeX
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