Simulated Biomechanics of the Lower Limb

As part of the Collaborative Research Centre 760 - "Biomechanics and Biology of Musculoskeletal Regeneration" - the goal of this project is to reconstruct patient specific 3D anatomy models of the human lower limb from medical image data. The central problem addressed by the Collaborative Research Centre (SFB) 760 initiative is the healing and regeneration of bone. The long term goal is the understanding of endogenous formation of biologically and mechanically competent bone. A key question to be answered is: "What are the physical mechanisms that allow the regeneration of such competent bone?" On the way to answering that question, patient specific musculoskeletal function and loading conditions have to be characterised. For that purpose, individual models of the lower limb anatomy are a basic prerequisite.