Virtual NeuroLab
This is a joint project with the department of Numerical Analysis and Modelling.
The goal of this joint research project is to gain insight into functional and anatomical properties of neuronal structures (currently in insects and vertebrates). This involves detailed comparisons of brain structures as well as examinations on the level of single neuron cells. We develop algorithms for the construction of geometric models from confocal microscopy image stacks. Based on these models we investigate innovative methods for generating atlases of brain structures, augmenting them with detail and integrating functional data. At the single neuron level, numerical simulations of these models and analysis of signal propagation are targeted at explaining functional roles of specific anatomic features of neurons.
Publications
2006 |
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Alexander Maye, Thomas Wenckebach, Hans-Christian Hege | Visualization, reconstruction, and integration of neuronal structures in digital brain atlases | Int. Journal of Neuroscience, Vol.116(4), pp. 431-459, 2006 |
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2005 |
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Robert Brandt, Torsten Rohlfing, Jürgen Rybak, Sabine Krofczik, Alexander Maye, Malte Westerhoff, Hans-Christian Hege, Randolf Menzel | A three-dimensional average-shape atlas of the honeybee brain and its applications | Journal of Comparative Neurology, Vol.492(1), pp. 1-19, 2005 |
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2003 |
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Malte (née Zöckler) | Efficient Visualization and Reconstruction of 3D Geometric from Neuro-Biological Confocal Microscope Scans | Doctoral thesis, Freie Universität Berlin, Peter Deuflhard (Advisor), 2003 |
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2002 |
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Malte Westerhoff, Alexander Maye, Robert Brandt, Randolf Menzel | 3D Geometry Reconstruction in Neuroanatomy | International Neuroscience Summit Abstract Book, p. 49, 2002 |
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Karlheinz Rein, Malte Zöckler, Michael T. Mader, Cornelia Grübel, Martin Heisenberg | The Drosophila Standard Brain | Current Biology, 12(3), pp. 227-231, 2002 |
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2001 |
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Malte Zöckler, Karlheinz Rein, Robert Brandt, Detlev Stalling, Hans-Christian Hege | Creating Virtual Insect Brains with Amira | ZIB-Report 01-32 |
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2000 |
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Malte Zöckler, Detlev Stalling, Hans-Christian Hege | Fast and Intuitive Generation of Geometric Shape Transitions | The Visual Computer, Vol.16(5), pp. 241-253, 2000 (preprint available as ) |
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