This is a joint project with the department of Numerical Analysis and Modelling.
The goal of this joint research project is to gain insight into functional and anatomical properties of neuronal structures (currently in insects and vertebrates). This involves detailed comparisons of brain structures as well as examinations on the level of single neuron cells. We develop algorithms for the construction of geometric models from confocal microscopy image stacks. Based on these models we investigate innovative methods for generating atlases of brain structures, augmenting them with detail and integrating functional data. At the single neuron level, numerical simulations of these models and analysis of signal propagation are targeted at explaining functional roles of specific anatomic features of neurons.

Publications

2006
Visualization, reconstruction, and integration of neuronal structures in digital brain atlases Int. Journal of Neuroscience, Vol.116(4), pp. 431-459, 2006 Alexander Maye, Thomas Wenckebach, Hans-Christian Hege BibTeX
Virtual NeuroLab
2005
A three-dimensional average-shape atlas of the honeybee brain and its applications Journal of Comparative Neurology, Vol.492(1), pp. 1-19, 2005 Robert Brandt, Torsten Rohlfing, Jürgen Rybak, Sabine Krofczik, Alexander Maye, Malte Westerhoff, Hans-Christian Hege, Randolf Menzel BibTeX
Virtual NeuroLab
2003
Efficient Visualization and Reconstruction of 3D Geometric from Neuro-Biological Confocal Microscope Scans Doctoral thesis, Freie Universität Berlin, Peter Deuflhard (Advisor), 2003 Malte (née Zöckler) BibTeX
Virtual NeuroLab
2002
3D Geometry Reconstruction in Neuroanatomy International Neuroscience Summit Abstract Book, p. 49, 2002 Malte Westerhoff, Alexander Maye, Robert Brandt, Randolf Menzel BibTeX
Virtual NeuroLab
The Drosophila Standard Brain Current Biology, 12(3), pp. 227-231, 2002 Karlheinz Rein, Malte Zöckler, Michael T. Mader, Cornelia Grübel, Martin Heisenberg BibTeX
DOI
Virtual NeuroLab
2001
Creating Virtual Insect Brains with Amira ZIB-Report 01-32 Malte Zöckler, Karlheinz Rein, Robert Brandt, Detlev Stalling, Hans-Christian Hege PDF
BibTeX
URN
Virtual NeuroLab
2000
Fast and Intuitive Generation of Geometric Shape Transitions The Visual Computer, Vol.16(5), pp. 241-253, 2000 (preprint available as ) Malte Zöckler, Detlev Stalling, Hans-Christian Hege BibTeX
DOI
Virtual NeuroLab