BovSys - Mathematical Modelling of Bovine Fertility and Metabolism
With modern technologies, vast amount of data are produced in experimental science. These data typically arise from the complex interplay of multiple biological...
Computation of Treatments for Infertility Related Endocrinological Diseases
Infertility affects 12% to 15% of reproductive age couples in Europe, costs approximately 1 billion Euros per year, and experts agree that these figures will double in a...
Model-based Spectrometer Calibration for Toxin Determination in Food
The company aokin produces and sells automatic analytic devices for the quantification of toxins in food. At present, the calibration of these devices is costly and time...
The company Förster-Technik GmbH Engen sells immunoassay-based measurement devices for the detection of progesterone in milk. These devices must be calibrated regularly...
Spectral clustering of Markov chain transition matrices with complex eigenvalues
Journal of Computational and Applied Mathematics, Vol.444, p. 115791, 2024
Anna-Simone Frank, Alexander Sikorski, Susanna RöblitzBibTeX arXiv DOI
Hormonal regulation of ovarian follicle growth in humans: Model-based exploration of cycle variability and parameter sensitivities
Journal of Theoretical Biology, 2022
Sophie Fischer-Holzhausen, Susanna RöblitzBibTeX DOI
Mathematical modelling of follicular growth and ovarian stimulation
Current Opinion in Endocrine and Metabolic Research, 2022
Sophie Fischer-Holzhausen, Susanna RöblitzBibTeX DOI
The androgen system across the menstrual cycle: Hormonal, (epi-)genetic and psychometric alterations
Physiology and Behavior, 2022
Tillmann Krüger, Brigitte Leeners, Enrico Tronci, Toni Mancini, Fabian Ille, Marcel Egli, Harald Engler, Susanna Röblitz, Helge Frieling, Christopher Sinke, Kirsten Jahn
BibTeX DOI
Modelling Oscillatory Patterns in the Bovine Estrous Cycle with Boolean Delay Equations
Bulletin of Mathematical Biology, 83(121), pp. 1-25, 2021
Mascha Berg, Julia Plöntzke, Heike Siebert, Susanna RöblitzBibTeX DOI
A Mathematical Model for the Influence of Glucose-Insulin Dynamics on the Estrous Cycle in Dairy Cows
ZIB-Report 19-22
Mohamed Omari, Alexander Lange, Julia Plöntzke, Susanna RöblitzPDF BibTeX URN
Combining in vitro simulation and in silico modelling towards a sophisticated human osteoarthritis model
Osteoarthritis and Cartilage, Vol.27, p. S183, 2019
Annemarie Lang, Lisa Fischer, Marie-Christin Weber, Timo Gaber, Rainald Ehrig, Susanna Röblitz, Frank Buttgereit
BibTeX DOI
In vitro and in silico modeling of cellular and matrix-related changes during the early phase of osteoarthritis
BioRxiv, 2019
Marie-Christin Weber, Lisa Fischer, Alexandra Damerau, Igor Ponomarev, Moritz Pfeiffenberger, Timo Gaber, Sebastian Götschel, Jens Lang, Susanna Röblitz, Frank Buttgereit, Rainald Ehrig, Annemarie Lang
BibTeX DOI
Modeling of Multivalent Ligand-Receptor Binding Measured by kinITC
Computation, 7(3), p. 46, 2019
Franziska Erlekam, Sinaida Igde, Susanna Röblitz, Laura Hartmann, Marcus WeberBibTeX DOI
A mathematical modelling approach to the insight of dynamic networks: Potassium homeostasis and glucose-insulin in dairy cows
ADSA 2018 Annual Meeting, Vol.101 Suppl. 2, pp. 226-227, American Dairy Science Association, Journal of Dairy Science, 2018
Julia Plöntzke, Mascha Berg, Susanna RöblitzBibTeX
Computing Personalised Treatments through In Silico Clinical Trials. A Case Study on Downregulation in Assisted Reproduction
Experimental Evaluation of Algorithms for Solving Problems with Combinatorial Explosion, Workshop of the Federated Logic Conference 2018 (FLoC 2018), Oxford, pp. 1-16, 2018
Toni Mancini, Federico Mari, Annalisa Massini, Igor Melatti, Ivano Salvo, Stefano Sinisi, Enrico Tronci, Rainald Ehrig, Susanna Röblitz, Brigitte Leeners
BibTeX DOI
Correspondence of Trap Spaces in Different Models of Bioregulatory Networks
SIAM Journal on Applied Dynamical Systems, 17(2), pp. 1742-1765, 2018 (preprint available as ZIB-Report 18-10)
Robert Schwieger, Heike Siebert, Susanna RöblitzPDF (ZIB-Report) BibTeX DOI
Generalized Markov State Modeling Method for Nonequilibrium Biomolecular Dynamics: Exemplified on Amyloid β Conformational Dynamics Driven by an Oscillating Electric Field
Journal of Chemical Theory and Computation, 14(7), pp. 3579-3594, 2018
Bernhard Reuter, Marcus Weber, Konstantin Fackeldey, Susanna Röblitz, Martin E. Garcia
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In silico Methods - Computational Alternatives to Animal Testing
ALTEX, 35(1), pp. 126-128, 2018
Annemarie Lang, Andrea Volkamer, Laura Behm, Susanna Röblitz, Rainald Ehrig, Marlon Schneider, Lisbet Geris, Joerg Wichard, Frank Buttgereit
BibTeX DOI
A dynamic model to simulate potassium balance in dairy cows
Journal of Dairy Science, 100(12), pp. 9799-9814, 2017 (preprint available as ZIB-Report 17-47)
Mascha Berg, Julia Plöntzke, Sabine Leonhard-Marek, Kerstin-Elisabeth Müller, Susanna RöblitzPDF (ZIB-Report) BibTeX DOI
Lack of association between female hormone levels and visuospatial working memory, divided attention and cognitive bias across two consecutive menstrual cycles
Front. Behav. Neurosci., 2017
Brigitte Leeners, Tillmann H. C. Krüger, Kirsten Geraedts, Enrico Tronci, Toni Mancini, Fabian Ille, Marcel Egli, Susanna Röblitz, Lanja Saleh, K. Spanhaus, Cordula Schippert, Y. Zhang, M. P. Hengartner
BibTeX DOI
Linear Precision Glycomacromolecules with Varying Interligand Spacing and Linker Functionalities Binding to Concanavalin A and the Bacterial Lectin FimH
Marcomolecular Bioscience, 17(12), p. 1700198, 2017
Sinaida Igde, Susanna Röblitz, Anne Müller, Katharina Kolbe, Sophia Boden, Claudia Fessele, Thisbe Lindhorst, Marcus Weber, Laura Hartmann
BibTeX DOI
Negative affect is unrelated to fluctuations in hormone levels across the menstrual cycle: evidence from a multisite observational study across two successive cycles
Journal of Psychosomatic Research, Vol.99, pp. 21-27, 2017
Michael Hengartner, Tillmann H. C. Krüger, Kirsten Geraedts, Enrico Tronci, Toni Mancini, Fabian Ille, Marcel Egli, Susanna Röblitz, Rainald Ehrig, Lanja Saleh, Katharina Spanaus, Cordula Schippert, Yuanyuan Zhang, Brigitte Leeners
BibTeX DOI
An integrative approach for model driven computation of treatments in reproductive medicine
BIOMAT - Proceedings of the 15th International Symposium on Mathematical and Computational Biology, Rorkee, India, 2016 (preprint available as ZIB-Report 16-04)
Rainald Ehrig, Thomas Dierkes, Stefan Schäfer, Susanna Röblitz, Enrico Tronci, Toni Mancini, Ivano Salvo, Vadim Alimguzhin, Federico Mari, Igor Melatti, Annalisa Massini, Tillmann H. C. Krüger, Marcel Egli, Fabian Ille, Brigitte Leeners
PDF (ZIB-Report) BibTeX
Follicular maturation in cows: mathematical models and data
10. European Conference on Mathematical and Theoretical Biology, 2016
Alexander Lange, Julia Plöntzke, Stefan Schäfer, Susanna RöblitzBibTeX
Mathematical Modelling of Follicular Maturation in Cows and Women
49. Jahrestagung der Physiologie und Pathologie der Fortpflanzung und gleichzeitig 41. Veterinär-Humanmedizinische Gemeinschaftstagung 2016, Leipzig., 2016 (epub ahead of print)
Stefan Schäfer, Julia Plöntzke, Susanna RöblitzBibTeX
Modelling of glucose-insulin metabolism and its effect on the estrous cycle in bovine
Annual Meeting of the Population Approach Group in Europe, 2016
Mohamed Omari, Julia Plöntzke, Mascha Berg, Susanna RöblitzBibTeX
A systems biology approach to bovine fertility and metabolism: Introduction of a glucose insulin model
15th International Symposium on Mathematical and Computational Biology, Rorkee, India, 2015 (preprint available as ZIB-Report 15-51)
Julia Plöntzke, Mascha Berg, Claudia Stötzel, Susanna RöblitzPDF (ZIB-Report) BibTeX
Complementing ODE-based System Analysis Using Boolean Networks Derived from an Euler-like Transformation
PLOS ONE, 2015 (preprint available as ZIB-Report 15-46)
Claudia Stötzel, Susanna Röblitz, Heike Siebert
PDF (ZIB-Report) BibTeX DOI
Identifying Multivalent Binding Kinetics of Precision Glycomacromolecules: A Kinetic Study Using kinITC
Münster Symposium on Cooperative Effects 2015 - SFB 858, at Westfälische Wilhelms-Universität Münster, 2015, 2015
Sinaida Igde, Hendrik Wölk, Susanna Röblitz, Marco Reidelbach, Marcus Weber, Laura Hartmann
BibTeX
Solution of the chemical master equation by radial basis functions approximation with interface tracking
BMC Systems Biology, 9(67), pp. 1-12, 2015
Ivan Kryven, Susanna Röblitz, Christof SchüttePDF BibTeX DOI
Advanced mathematical modeling in systems biology
MATHEON-Mathematics for Key Technologies, Vol.1, pp. 29-44, Peter Deuflhard, Martin Grötschel, Dietmar Hömberg, Jürg Kramer, Volker Mehrmann, Konrad Polthier, Frank Schmidt, Christof Schütte, Martin Skutela, Jürgen Sprekels (Eds.), European Mathematical Society, 2014
Alexander Bockmayr, Heike Siebert, Susanna Röblitz, Christof Schütte, Peter Deuflhard
BibTeX
Exploration of different wave patterns in a model of the bovine estrous cycle by Fourier analysis
BIOMAT - Proceedings of the 14th International Symposium on Mathematical and Computational Biology, Bedlewo, Poland, 2014 (preprint available as ZIB-Report 16-02)
Claudia Stötzel, Rainald Ehrig, H. Marike T. Boer, Julia Plöntzke, Susanna RöblitzPDF (ZIB-Report) BibTeX
Mathematische Modellierung metabolischer Einflussfaktoren auf den Milchkuhzyklus
Master's thesis, Humboldt-Universität zu Berlin, Susanna Röblitz, Caren Tischendorf (Advisors), 2014
Jane Knöchel
PDF BibTeX URN
Modeling of the BMP mediated co-regulation of the Smad and Non-Smad pathways in the context of cell density
10th International BMP conference, 2014, Berlin, Germany, 2014
Pooja Gupta, Carola Krause, Paul Rikeit, Susanna Röblitz, Petra Knaus, Christof SchütteBibTeX
Patient-Specific Models from Inter-Patient Biological Models and Clinical Records
Proceedings of the 14th Conference on Formal Methods in Computer-Aided Design (FMCAD 2014), pp. 207-214, 2014
Toni Mancini, Ivano Salvo, Federico Mari, Igor Melatti, Annalisa Massini, Stefano Sinisi, Enrico Tronci, Francesco Davi, Thomas Dierkes, Rainald Ehrig, Susanna Röblitz, Brigitte Leeners, Tillmann H. C. Krüger, Marcel Egli, Fabian Ille
BibTeX
A mathematical model of the human menstrual cycle for the administration of GnRH analogues
Journal of Theoretical Biology, Vol.321, pp. 8-27, 2013 (preprint available as ZIB-Report 11-16)
Susanna Röblitz, Claudia Stötzel, Peter Deuflhard, Hannah M. Jones, David-Olivier Azulay, Piet van der Graaf, Steven Martin
PDF (ZIB-Report) BibTeX DOI
Adaptive spectral clustering with application to tripeptide conformation analysis
The Journal of Chemical Physics, Vol.139, pp. 110-194, 2013
Fiete Haack, Konstantin Fackeldey, Susanna Röblitz, Olga Scharkoi, Marcus Weber, Burkhard Schmidt
BibTeX DOI
Fuzzy spectral clustering by PCCA+: application to Markov state models and data classification
Advances in Data Analysis and Classification, 7(2), pp. 147-179, 2013
Susanna Röblitz, Marcus WeberBibTeX DOI
Mathematical modeling of the Smad and Non-Smad BMP signaling pathways in context of cell density
Computational Models in biology and medicine, 2013, Dresden, Germany, 2013
Pooja Gupta, Susanna Röblitz, Carola Krause, Petra Knaus, Christof SchütteBibTeX
Parameter identification in large kinetic networks with BioPARKIN
CoRR - Computing Research Repository - arXiv.org, Vol.abs/1303.4928, 2013
Thomas Dierkes, Susanna Röblitz, Moritz Wade, Peter DeuflhardPDF BibTeX
A differential equation model to investigate the dynamics of the bovine estrous cycle
Advances in Systems Biology, pp. 597-606, 2012
H. Marike T. Boer, Claudia Stötzel, Susanna Röblitz, Henri Woelders
BibTeX DOI
Advances in modelling of the bovine estrous cycle: Synchronization with PGF2alpha
Theriogenology, Vol.78, pp. 1415-1428, 2012 (preprint available as ZIB-Report 11-17)
Claudia Stötzel, Julia Plöntzke, Wolfgang Heuwieser, Susanna RöblitzPDF (ZIB-Report) BibTeX DOI
A simple mathematical model of the bovine estrous cycle
Journal of Theoretical Biology, 278(1), pp. 20-31, 2011 (preprint available as ZIB-Report 10-06)
H. Marike T. Boer, Claudia Stötzel, Susanna Röblitz, Peter Deuflhard, Roel F. Veerkamp, Henri Woelders
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Mechanisms regulating follicle wave patterns in the bovine estrous cycle investigated with a mathematical model
Journal of Dairy Science, 94(12), pp. 5987-6000, 2011
H. Marike T. Boer, Susanna Röblitz, Claudia Stötzel, Roel F. Veerkamp, Bas Kemp, Henri Woelders
BibTeX DOI
Adaptive Spectral Clustering for Conformation Analysis
AIP Conference Proceedings, 1281(1), pp. 1585-1588, 2010
Fiete Haack, Susanna Röblitz, Olga Scharkoi, Burkhard Schmidt, Marcus WeberBibTeX DOI
Mathematical Systems Biology at Zuse Institute Berlin (ZIB)
BioTOPics - Journal of Biotechnology in Berlin-Brandenburg, Vol.39, 2010
Peter Deuflhard, Susanna Röblitz, Claudia Stötzel
BibTeX
Fuzzy Spectral Clustering by PCCA+
Classification and Clustering: Models, Software and Applications, pp. 73-79, 2009
Susanna Röblitz, Marcus WeberBibTeX
Statistical Error Estimation and Grid-free Hierarchical Refinement in Conformation Dynamics
Doctoral thesis, Freie Universität Berlin, Peter Deuflhard, Wilhelm Huisinga (Advisors), 2009
Susanna RöblitzPDF BibTeX URN
Computation of equilibrium densities in metastable dynamical systems by domain decomposition
Numerical Analysis and Applied Mathematics, International Conference on Numerical Analysis and Applied Mathematics 2008, pp. 339-342, Vol.1048, 2008
Susanna Kube, Marcus WeberBibTeX
Monte Carlo sampling of Wigner functions and surface hopping quantum dynamics
Journal of Computational Physics, 228(6), pp. 1947-1962, 2008 (preprint available as ZIB-Report 07-17)
Susanna Kube, Caroline Lasser, Marcus WeberPDF (ZIB-Report) BibTeX DOI
Preserving the Markov Property of Reduced Reversible Markov Chains
Numerical Analysis and Applied Mathematics, International Conference on Numerical Analysis and Applied Mathematics 2008, pp. 593-596, Vol.1048, 2008
Susanna Kube, Marcus WeberBibTeX
A Coarse Graining Method for the Identification of Transition rates between Molecular Conformations
Journal of Chemical Physics, 126(2), 2007
Susanna Kube, Marcus WeberBibTeX DOI
Stable Computation of Probability Densities of Metastable Dynamical Systems
SIAM J. Multiscale Model. Simul., 6(2), pp. 396-416, 2007
Marcus Weber, Susanna Kube, Lionel Walter, Peter DeuflhardBibTeX
Coarse Grained Molecular Kinetics
ZIB-Report 06-35 (Appeared as : "A coarse grained method for the identification of transition rates between molecular conformations" in Journal of Chemical Physics, 126(2) 2007)
Susanna Kube, Marcus WeberPDF BibTeX URN
Efficient Sampling of the Stationary Distribution of Metastable Dynamical Systems
ZIB-Report 07-03
Marcus Weber, Susanna Kube, Alexander Riemer, Alexander Bujotzek
PDF BibTeX URN
Stable computation of probability densities for metastable dynamical systems
ZIB-Report 06-39 (Appeared in: SIAM J. Multisc. Mod. Sim. 2007, 6(2), pp. 396-416)
Marcus Weber, Lionel Walter, Susanna Kube, Peter DeuflhardPDF BibTeX URN
Robust Perron Cluster Analysis for Various Applications in Computational Life Science
Computational Life Sciences, pp. 57-66, 2005
Marcus Weber, Susanna KubeBibTeX