During the Berlin Science Week 2025, Director of the Barcelona Supercomputing Center Mateo Valero and the President of the Zuse Institute Berlin, Christof Schütte, discussed the present and future of supercomputing in Europe. Approaching the topic from complementary perspectives, they addressed the scientific and technological challenges of High-Performance Computing (HPC). The conversation was moderated by Guillermo Pérez-Hernández, a computational chemist and CERFA member.