Imaging and analyzing the entire brain of small vertebrates at maximal confocal microscopy resolution seems possible today. One could, for example, derive a complete distribution of neuron cell bodies; screen for unlocalized changes, such as amyloid plaques; or build detailed anatomical reference systems. The goal of this project is to develop an image acquisition and processing pipeline for entire brains and apply it to a mouse brain.
Group
Heads
Partners
Max Planck Florida Institute (M. Oberlaender, H.S. Meyer, B. Sakmann)
Funding
MPI