We study synchronization due to noise and/or coupling in dynamical systems with multiple time scales. The challenge of taming nonuniformly hyperbolic structures is faced with non-standard geometric singular perturbation theory. An application focus is on biochemical oscillation reactions, with potential scope for wave fronts under noise.

pH-dependent reaction kinetics

The 4-variable model under consideration includes substrate transformation, product outflow, and exchange with the environment. Reaction rates are strongly influenced by pH-values.  

Figure 1: Urea−urease reaction confined to lipid vesicles

Publications

2024
Excluded volume induces buckling in optically driven colloidal rings Phys. Rev. Research, Vol.6, p. L012044, 2024 Eric Cereceda-López, Mattia Ostinato, Antonio Ortiz-Ambriz, Arthur Straube, Matteo Palassini, Pietro Tierno BibTeX
arXiv
DOI
Synchronization and Geometric Structures of Stochastic Biochemical Oscillators
2023
Accurate reduced models for the pH oscillations in the urea-urease reaction confined to giant lipid vesicles The Journal of Physical Chemistry B, 127(13), pp. 2955-2967, 2023 (preprint available as ZIB-Report 22-21) Arthur Straube, Stefanie Winkelmann, Felix Höfling PDF (ZIB-Report)
BibTeX
arXiv
DOI
Synchronization and Geometric Structures of Stochastic Biochemical Oscillators
2021
Stochastic pH oscillations in a model of the urea–urease reaction confined to lipid vesicles J. Phys. Chem. Lett., Vol.12, pp. 9888-9893, 2021 Arthur Straube, Stefanie Winkelmann, Christof Schütte, Felix Höfling BibTeX
DOI
Synchronization and Geometric Structures of Stochastic Biochemical Oscillators