AA1-19 Drug Candidates as Pareto Optima in Chemical Space
The search for novel drug candidates that, at the same time, act with high efficacy, comply with defined chemical properties, and also show low off-target effects can be...
Synchronization and Geometric Structures of Stochastic Biochemical Oscillators
We study synchronization due to noise and/or coupling in dynamical systems with multiple time scales. The challenge of taming nonuniformly hyperbolic structures is faced...
This project aims at the creation of a MATH+ success story around the mathematics of drug design. It proposes a new drug design strategy for G-protein coupled receptors...
Concentration Effects and Collective Variables in Agent-Based Systems
Agent-based models (ABMs) are often high-dimensional and complex, making simulations costly and formal analysis hard. Low-dimensional model reduction is hence of great...
