Within this project, the development of a methodology for the patient specific analysis of cerebral aneurysms is in focus. Such a cerebral aneurysm is potentially life-threatening. Every year, about 10 out of 100,000 people suffer a spontaneous rupture, with a mortality of 50%. For the patients and their attending physicians, a sensible estimation of the rupture risk and the best strategy of treatment is of great importance. We hypothesize that an analysis based on the individual geometry of an aneurysm, and the predicted biofluidmechanical properties can provide insight into this matter. Here, we especially deal with the segmentation, reconstruction and visualization of aneurysms as well as of the analysis of blood flows.

Publications

2016
Turbulence in blood damage modeling The International Journal of Artificial Organs, 39(4), pp. 147-210, 2016 Leonid Goubergrits, Jan Osman, Ricardo Mevert, Ulrich Kertzscher, Kai Pöthkow, Hans-Christian Hege BibTeX
DOI
Patient-specific Analysis of the Hemodynamics of Cerebral Aneurysms
2014
In vitro study of hemodynamic treatment improvement: Hunterian ligation of a fenestrated basilar artery aneurysm after coiling The International Journal of Artificial Organs, 37(4), pp. 325-335, 2014 Leonid Goubergrits, Andreas Spuler, Jens Schaller, Nils Wiegmann, Andre Berthe, Hans-Christian Hege, Klaus Affeld, Ulrich Kertzscher BibTeX
DOI
Patient-specific Analysis of the Hemodynamics of Cerebral Aneurysms
2013
Nonparametric Models for Uncertainty Visualization Computer Graphics Forum, 32(3), pp. 131-140, 2013 Kai Pöthkow, Hans-Christian Hege PDF
BibTeX
DOI
Patient-specific Analysis of the Hemodynamics of Cerebral Aneurysms
Reproducibility of Image-Based Analysis of Cerebral Aneurysm Geometry and Hemodynamics: An In-Vitro Study of Magnetic Resonance Imaging, Computed Tomography, and Three-Dimensional Rotational Angiography Journal of Neurological Surgery, Part A: Central European Neurosurgery, 74(5), pp. 294-302, 2013 Leonid Goubergrits, Jens Schaller, Ulrich Kertzscher, Christoph Petz, Hans-Christian Hege, Andreas Spuler BibTeX
DOI
Patient-specific Analysis of the Hemodynamics of Cerebral Aneurysms
2012
Probabilistic Local Features in Uncertain Vector Fields with Spatial Correlation Computer Graphics Forum, 31(3), pp. 1045-1054, 2012 Christoph Petz, Kai Pöthkow, Hans-Christian Hege PDF
BibTeX
Patient-specific Analysis of the Hemodynamics of Cerebral Aneurysms
Statistical wall shear stress maps of ruptured and unruptured middle cerebral artery aneurysms J. R. Soc. Interface, 9(69), pp. 677-688, 2012 Leonid Goubergrits, Jens Schaller, Ulrich Kertzscher, Nils van den Bruck, Kai Pöthkow, Christoph Petz, Hans-Christian Hege, Andreas Spuler PDF
BibTeX
DOI
Patient-specific Analysis of the Hemodynamics of Cerebral Aneurysms
2010
In Vitro Study of Near-Wall Flow in a Cerebral Aneurysm Model with and without Coils American Journal of Neuroradiology, Vol.31:8, pp. 1521-1528, 2010 Leonid Goubergrits, Bente Thamsen, André Berthe, Jens Poethke, Ulrich Kertzscher, Klaus Affeld, Christoph Petz, Hans-Christian Hege, Heinrich Hoch, Andreas Spuler BibTeX
DOI
Patient-specific Analysis of the Hemodynamics of Cerebral Aneurysms