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Home Research ENT-Surgery Under Consideration of Optimal Nasal Air Flow

ENT-Surgery under Consideration of Optimal Nasal Air Flow

Our objective is to analyze and understand the physiology and patho-physiology of normal nasal breathing. To this end, airflow simulations based on computational fluid dynamics (CFD) are conducted for a highly detailed anatomy of the upper respiratory tract from the external nose deep into the trachea, including frontal and maxillary sinuses, as well as the ethmoid. Complex flow phenomena are investigated with regard to individual anatomy and its variations. We are aiming to gain insight into the relationship between morphology and flow behaviour in order to provide general treatment proposals and to develop computer assisted planning tools for decision support in functional rhinosurgery.

ENT-Surgery under Consideration of Optimal Nasal Air Flow
Group
Computational Diagnosis and Therapy Planning
Heads
Zachow, Dr. Stefan
Hildebrandt, Dr. Thomas
Members
Kuhn, Dr. Alexander
Partners
Limmatklinik, Zürich (Th. Hildebrandt)
CFX Berlin Software GmbH (P. Bartsch, A. Steinmann)
Klinikum Karlsruhe, HNO-Klinik (W. Heppt)
Charité Berlin, Biofluid Mechanics Lab (L. Goubergrits)
Funding
Klinikum Karlsruhe
Asklepios Klinik Birkenwerder
ZIB

Publications

2020
Characterization of the Airflow within an Average Geometry of the Healthy Human Nasal Cavity Scientific Reports, 3755(10), 2020 Jan Brüning, Thomas Hildebrandt, Werner Heppt, Nora Schmidt, Hans Lamecker, Angelika Szengel, Natalja Amiridze, Heiko Ramm, Matthias Bindernagel, Stefan Zachow, Leonid Goubergrits BibTeX
DOI
Morphological indicators for limitations in nasal breathing Bachelor's thesis, Freie Universität Berlin, Stefan Zachow, Heiko Ramm (Advisors), 2020 Natalja Amiridze BibTeX
2019
Digital Analysis of Nasal Airflow Facilitating Decision Support in Rhinosurgery Facial Plastic Surgery, 35(1), pp. 1-8, 2019 Thomas Hildebrandt, Jan Joris Bruening, Hans Lamecker, Stefan Zachow, Werner Heppt, Nora Schmidt, Leonid Goubergrits BibTeX
DOI
Generation and Visual Exploration of Medical Flow Data: Survey, Research Trends, and Future Challenges Computer Graphics Forum, 38(1), pp. 87-125, 2019 Steffen Oeltze-Jaffra, Monique Meuschke, Mathias Neugebauer, Sylvia Saalfeld, Kai Lawonn, Gabor Janiga, Hans-Christian Hege, Stefan Zachow, Bernhard Preim BibTeX
DOI
The Healthy Nasal Cavity - Characteristics of Morphology and Related Airflow Based on a Statistical Shape Model Viewed from a Surgeon’s Perspective Facial Plastic Surgery, 35(1), pp. 9-13, 2019 Thomas Hildebrandt, Jan Joris Bruening, Nora Laura Schmidt, Hans Lamecker, Werner Heppt, Stefan Zachow, Leonid Goubergrits BibTeX
DOI
2017
Numerical Analysis of Nasal Breathing - A Pilot Study Facial Plastic Surgery, 33(4), pp. 388-395, 2017 Jan Brüning, Leonid Goubergrits, Werner Heppt, Stefan Zachow, Thomas Hildebrandt BibTeX
DOI
2013
Evaluation of the Intranasal Flow Field through Computational Fluid Dynamics (CFD) Journal of Facial and Plastic Surgery, 29(2), pp. 93-98, 2013 Thomas Hildebrandt, Leonid Goubergrits, Werner Heppt, Stefan Bessler, Stefan Zachow BibTeX
DOI
2011
Das Konzept der Rhinorespiratorischen Homöostase – ein neuer theoretischer Ansatz für die Diskussion physiologischer und physikalischer Zusammenhänge bei der Nasenatmung Doctoral thesis, Albert-Ludwigs-Universität Freiburg, Werner Heppt, Stefan Zachow (Advisors), 2011 Thomas Hildebrandt BibTeX
2009
Generierung hybrider Gitter für die Strömungssimulation auf komplexen anatomischen Geometrien Master's thesis, Technische Universität Berlin, Marc Alexa, Stefan Zachow (Advisors), 2009 Bertram Wölk PDF
BibTeX
URN
Visual Exploration of Nasal Airflow IEEE Transactions on Visualization and Computer Graphics, 15(8), pp. 1407-1414, 2009 Stefan Zachow, Philipp Muigg, Thomas Hildebrandt, Helmut Doleisch, Hans-Christian Hege BibTeX
DOI
2008
Breathing Easily: Simulation of airflow in human noses can become a useful rhinosurgery planning tool ANSYS Advantage, Vol.Vol. II, No. 1, pp. 30-31, 2008 Alexander Steinmann, Peter Bartsch, Stefan Zachow, Thomas Hildebrandt BibTeX
2007
3D reconstruction of individual anatomy from medical image data: Segmentation and geometry processing ZIB-Report 07-41 (Appeared on CD-ROM: 25. ANSYS Conference & CADFEM Users' Meeting, Dresden, 2007, Proc. CD 2.12.15) Stefan Zachow, Michael Zilske, Hans-Christian Hege PDF
BibTeX
URN
Aesthetic and Function in Rhinoplasty Springer Journal, Vol.264 (Suppl 1), RL 126, p. 307, 2007 Werner Heppt, Thomas Hildebrandt, Alexander Steinmann, Stefan Zachow BibTeX
Innovation in der Funktionell-Ästhetischen Nasenchirurgie: Rhino-CFD Face, Int. Mag. of Orofacial Esthetics, pp. 20-23, 2007 Thomas Hildebrandt, Stefan Zachow, Alexander Steinmann, Werner Heppt BibTeX
Understanding nasal airflow via CFD simulation and visualization Proc. Computer Aided Surgery around the Head, pp. 173-176, 2007 Stefan Zachow, Alexander Steinmann, Thomas Hildebrandt, Werner Heppt BibTeX
2006
CFD simulation of nasal airflow: Towards treatment planning for functional rhinosurgery Int. J. of Computer Assisted Radiology and Surgery, pp. 165-167, 2006 Stefan Zachow, Alexander Steinmann, Thomas Hildebrandt, Rainer Weber, Werner Heppt BibTeX