As part of the Collaborative Research Centre 760 - "Biomechanics and Biology of Musculoskeletal Regeneration" - the goal of this project is to reconstruct patient specific 3D anatomy models of the human lower limb from medical image data. The central problem addressed by the Collaborative Research Centre (SFB) 760 initiative is the healing and regeneration of bone. The long term goal is the understanding of endogenous formation of biologically and mechanically competent bone. A key question to be answered is: "What are the physical mechanisms that allow the regeneration of such competent bone?" On the way to answering that question, patient specific musculoskeletal function and loading conditions have to be characterised. For that purpose, individual models of the lower limb anatomy are a basic prerequisite.

Publications

2017
Pelvic and lower extremity physiological cross-sectional areas: An MRI study of the living young and comparison to published research literature Surgical and Radiologic Anatomy, 39(8), pp. 849-857, 2017 Juliane Lube, Natasha Flack, Sebastian Cotofana, Orkun Özkurtul, Stephanie Woodley, Stefan Zachow, Niels Hammer BibTeX
DOI
Simulated Biomechanics of the Lower Limb
2013
Articulated Statistical Shape Models Master's thesis, Humboldt-Universität zu Berlin, Beate Meffert (Advisor), 2013 Matthias Bindernagel BibTeX
Simulated Biomechanics of the Lower Limb
Deformable Meshes for Accurate Automatic Segmentation of Medical Image Data Doctoral thesis, Universität zu Lübeck, Bernd Fischer †, Jan Modersitzki (Advisors), 2013 Dagmar Kainmüller BibTeX
Simulated Biomechanics of the Lower Limb
2011
An Articulated Statistical Shape Model of the Human Knee Bildverarbeitung für die Medizin 2011, pp. 59-63, 2011 Matthias Bindernagel, Dagmar Kainmüller, Heiko Seim, Hans Lamecker, Stefan Zachow, Hans-Christian Hege BibTeX
DOI
Simulated Biomechanics of the Lower Limb
2010
Improving Deformable Surface Meshes through Omni-directional Displacements and MRFs Proc. Medical Image Computing and Computer Assisted Intervention (MICCAI), Tianzi Navab, Josien P. W. Pluim, Max Viergever (Eds.), pp. 227-234, Vol.6361, Lecture Notes in Computer Science, 2010 Dagmar Kainmüller, Hans Lamecker, Heiko Seim, Stefan Zachow, Hans-Christian Hege BibTeX
DOI
Simulated Biomechanics of the Lower Limb
Model-based Auto-Segmentation of Knee Bones and Cartilage in MRI Data Proc. MICCAI Workshop Medical Image Analysis for the Clinic, B. v. Ginneken (Ed.), pp. 215-223, 2010 Heiko Seim, Dagmar Kainmüller, Hans Lamecker, Matthias Bindernagel, Jana Malinowski, Stefan Zachow BibTeX
Simulated Biomechanics of the Lower Limb
2009
A System for Unsupervised Extraction of Orthopaedic Parameters from CT Data GI Workshop Softwareassistenten - Computerunterstützung für die medizinische Diagnose und Therapieplanung, pp. 1328-1337, GI-Edition Lecture Notes in Informatics, 2009 Heiko Seim, Dagmar Kainmüller, Hans Lamecker, Stefan Zachow BibTeX
Simulated Biomechanics of the Lower Limb
An Articulated Statistical Shape Model for Accurate Hip Joint Segmentation EBMC 2009. Int. Conf. of the IEEE Eng. in Med. and Biol. Society (EMBC), pp. 6345-6351, 2009 Dagmar Kainmüller, Hans Lamecker, Stefan Zachow, Hans-Christian Hege BibTeX
Simulated Biomechanics of the Lower Limb
Automatic Extraction of Anatomical Landmarks from Medical Image Data: An Evaluation of Different Methods Proc. of IEEE Int. Symposium on Biomedical Imaging (ISBI), pp. 538-541, 2009 Heiko Seim, Dagmar Kainmüller, Markus O. Heller, Stefan Zachow, Hans-Christian Hege BibTeX
Simulated Biomechanics of the Lower Limb
Multi-object Segmentation with Coupled Deformable Models Annals of the British Machine Vision Association (BMVA), Vol.5, pp. 1-10, 2009 Dagmar Kainmüller, Hans Lamecker, Stefan Zachow BibTeX
Simulated Biomechanics of the Lower Limb
Multi-object segmentation of head bones MIDAS Journal, 2009 Dagmar Kainmüller, Hans Lamecker, Heiko Seim, Stefan Zachow BibTeX
Simulated Biomechanics of the Lower Limb
2008
Coupling Deformable Models for Multi-object Segmentation Proc. Int. Symp. on Computational Models for Biomedical Simulation (ISBMS), pp. 69-78, Springer LNCS 5104, 2008 Dagmar Kainmüller, Hans Lamecker, Stefan Zachow, Hans-Christian Hege BibTeX
DOI
Simulated Biomechanics of the Lower Limb
Multi-Object Segmentation with Coupled Deformable Models Proc. Medical Image Understanding and Analysis, pp. 34-38, 2008 Dagmar Kainmüller, Hans Lamecker, Stefan Zachow, Markus O. Heller, Hans-Christian Hege BibTeX
Simulated Biomechanics of the Lower Limb