Computational research and data science are revolutionizing the field of medicine. ZIB covers a broad range of activities such as the development of novel methods for enabling the simulation and prediction of drug interactions, allowing for more efficient and targeted drug design processes, or of the design of new techniques for analyzing vast amounts of biological and clinical data to uncover patterns, predict disease outcomes, and identify potential drug targets. Furthermore, our researchers are involved in the development of personalized medicine by integrating patient-specific data to tailor treatments, optimize healthcare outcomes, and enhance overall patient care in the realm of digital health.

MATH+ AA1-20

Geometric Learning for Single-Cell RNA Velocity Modeling

Biological cells undergo state transitions, measurable with single-cell RNA sequencing. RNA velocity estimates gene expression change rates, forming velocity vectors...

Geometric Learning for Single-Cell RNA Velocity Modeling
AA1-19 Drug Candidates as Pareto Optima in Chemical Space

AA1-19 Drug Candidates as Pareto Optima in Chemical Space

Die Suche nach Wirkstoffkandidaten mit geringen Nebenwirkungen kann als ein multiobjektiven Optimierungsproblem (MOOP) im chemischen Raum interpretiert werden. Mittels...

AA1-19 Drug Candidates as Pareto Optima in Chemical Space
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Manifold-Valued Graph Neural Networks

Geometry-aware, data-analytic approaches improve understanding and assessment of pathophysiological processes. We will derive a new theoretical framework for deep neural...

Manifold-Valued Graph Neural Networks
Human

Individualized Morphological Analysis of the Human Spine

The causes of low back pain are not yet fully understood. One essential part of a better understanding is the knowledge about the relationship between spinal morphology... Individualized Morphological Analysis of the Human Spine
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MODAL-MedLab

Changes in cells while they are undergoing transformation from "normal" to malignant cells (e.g. during infections) happen on many biological levels, such as genome...

MODAL-MedLab
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Reduced Basis Methods in Orthopedic Hip Surgery Planning

This project aims at the development, analysis and implementation of algorithms for computer-assisted planning in hip surgery and hip joint replacement by fast virtual... Reduced Basis Methods in Orthopedic Hip Surgery Planning
MODAL

Research Campus MODAL

The Forschungscampus ("Research Campus") MODAL is a platform for a public-private innovation partnership established by ZIB and Freie Universität Berlin together with... Research Campus MODAL